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      confOrganiser.com - Work: CHEMICAL ASPECTS OF RADIOPHARMACEUTICALS APPLICATIONS IN DIAGNOSIS AND THERAPY

CHEMICAL ASPECTS OF RADIOPHARMACEUTICALS APPLICATIONS IN DIAGNOSIS AND THERAPY

1. Emir Horozić, Univerzitet u Tuzli, Tehnološki fakultet, Federation of Bosnia and Herzegovina , Bosnia and Herzegovina
2. Amira Cipurković, Univerzitet u Tuzli, Federation of Bosnia and Herzegovina , Bosnia and Herzegovina

Diagnosis and treatment of pathological conditions of various organs, primarily malignant diseases, includes the use of suitable radionuclides or radiopharmaceuticals. The discovery of radioactivity opened wide applications of radionuclides in medicine. The advantages of the application of radionuclides in diagnosis of pathological conditions are their applications in very low concentrations and not expressed pharmacokinetic effects on biological systems, but high sensitivity at the same time. The basic principle for the application of radionuclides in therapy is selective deposition of certain radiation doses in tissues or organs to be treated. The effectiveness of radiation therapy depends on several factors: physical and chemical properties of radionuclides that are used, the localization of the tumor, blood circulation, health status of the patient and so on.
In this paper we made review of some of the most important radionuclides, such as 131I, 89Sr, 32P, 153Sm, 186Re, 213Bi, 99mTc and others that are used in the diagnosis and treatment of a wide range of diseases, as well as the chemical forms and indications for its use.

Key words :

Thematic field: Teorijska i primijenjena hemija

Date: 18.10.2016.

XI Savjetovanje hemičara, tehnologa i ekologa Republike Srpske

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